Fibrin Glue Usage Increasing in Surgical Procedures
Fibrin glue, also known as fibrin tissue adhesive or fibrin sealant, comprises fibrinogen (lyophilized pool human concentrate), thrombin (bovine, reconstituted with calcium chloride), and sometimes antifibrinolytic agents and factor XIII. It is primarily used for sealing tissues, healing of wounds, coagulating blood, and stopping hemorrhage. Optimum benefits are achieved when fibrin glue is combined with bolus infusions of factor concentrate. In contemporary times, these sealants are generally used to offer effective tissue adherence and improve local surgical hemostasis.
Owing to their tissue adhesiveness, elastic property, and tensile strength, plasma fibrin sealants have become a vital adjunct in microsurgical procedures. These properties have increased the application of this glue in cardiac surgeries, vascular surgeries, general surgeries, lacerations of spleen and liver, neurosurgeries, wound management, burn bleeding, plastic surgeries, and orthopedic surgeries. The surging incidence of these procedures will accelerate the fibrin glue market at a CAGR of 10.9% during the forecast period (2017–2023).
In recent years, cosmetic surgeries have seen a significant spike due to the high consumer awareness about plastic surgeries and personal appearance and the constant technological developments in surgical procedures. The International Society of Aesthetic Plastic Surgery (ISAPS) states that 821,890 rhinoplasty procedures, 924,031 abdominoplasty procedures, 1,259,839 eyelid surgeries, 1,704,786 liposuction surgeries, and 1,795,551 breast augmentation procedures were performed in 2018, globally. These surgeries involve alteration, restoration, and reconstruction of the human body parts. Medical professionals use fibrin glue during these surgical procedures to prevent any marks of surgeries.
Globally, North America is the leader in the fibrin glue market. This is majorly due to the surge in cardiac surgeries and plastic surgeries. For instance, according to the Centers for Disease Control and Prevention (CDC), the U.S. records at least one cardiovascular disease (CVD)-related death every 36 seconds. Further, the American Society of Plastic Surgery (ASPS) states that the U.S. registered 1.8 million cosmetic surgical procedures in 2019. Moreover, the vast population of the elderly and huge healthcare expenditure have also fueled the consumption of fibrin glue in the region.
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